Legless Southern inventor Dr. Arliss Loveless plans to rekindle the Civil War by assassinating President Ulysses S. Grant. Only two men can stop him: gunfighter James West and master-of-disguise and inventor Artemus Gordon. The two must team up to thwart Loveless' plans.

Cast: Will Smith, Kevin Kline, Kenneth Branagh, Salma Hayek Pinault, M. Emmet Walsh, Ted Levine