UFC 268: Usman vs. Covington 2 was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on November 6, 2021, at Madison Square Garden in New York City, New York, United States. A UFC Welterweight Championship rematch between the current champion Kamaru Usman (also The Ultimate Fighter: American Top Team vs. Blackzilians welterweight winner) and former interim champion Colby Covington headlined the event.

Cast: Kamaru Usman, Colby Covington, Rose Namajunas, Zhang Weili, Marlon Vera, Frankie Edgar